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Ateries MAP

A handy map showing where your arteries are and how they are connected

What is FMD Poster

A poster produced by FMDCHAT.org, please print and share with work places and hospitals

August 31, 2011

Diagnosing and Treating Atypical Arterial Pathologies of Aortic Arch Vessels: Dissection and Fibromuscular Dysplasia

Although rare, pathologies of the aortic arch vessels can result in devastating sequelae. This article will address two of these pathologies, fibromuscular dysplasia and arterial dissection, along with diagnosis and treatment options.

January 31, 2013

Shared associations of nonatherosclerotic, largevessel, cerebrovascular arteriopathies: considering intracranial aneurysms, cervical artery dissection, moyamoya disease and fibromuscular dysplasia

With ongoing advancements in noninvasive vascular imaging and high-throughput genomics, we have

the opportunity to reclassify the cerebrocervical disorders by these shared associations, rather than their

downstream events, and to better understand etiology, mechanism and preventive treatments going

forward.

March 11, 2013

A Report of the United States Registry for Fibromuscular Dysplasia

Clinical Manifestations of Fibromuscular Dysplasia Vary by Patient Sex: A Report of the

United States Registry for Fibromuscular Dysplasia

December 18, 2014

Recent Developments in the Understanding and Management of Fibromuscular Dysplasia

This report presented the lasses information in the understanding of FMD

March 03, 2014

AHA Scientific Statement

 

Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions A Scientific Statement From the American Heart Association

April 13, 2014

Clinical and biochemical profiles suggest fibromuscular dysplasia is a systemic disease with altered TGF-

Fibromuscular dysplasia (FMD) is a rare, nonatherosclerotic arterial disease for which the molecular basis is unknown. We comprehensively studied 47 subjects with FMD, including physical examination, spine magnetic resonance imaging, bone densitometry, and brain magnetic resonance angiography. Inflammatory biomarkers in plasma and transforming growth factor   (TGF- ) cytokines in patient-derived dermal fibroblasts were measured by ELISA. Arterial pathology other than medial fibrodysplasia with multifocal stenosis included cerebral aneurysm, found in 12.8% of subjects. Extra-arterial pathology included low bone density (P< 0.001); early onset degenerative spine disease (95.7%); increased incidence of Chiari I malformation (6.4%) and dural ectasia (42.6%); and physical examination findings of a mild connective tissue dysplasia (95.7%). Screening for mutations causing known genetically mediated arteriopathies was unrevealing. We found elevated plasma TGF- 1 (P 0.009), TGF- 2 (P 0.004) and additional inflammatory markers, and increased TGF- 1 (P 0.0009) and TGF- 2 (P 0.0001) secretion in dermal fibroblast cell lines from subjects with FMD compared to age- and gender-matched controls. Detailed phenotyping of patients with FMD allowed us to demonstrate that FMD is a systemic disease with alterations in common with the spectrum of genetic syndromes that involve altered TGF-  signaling

and offers TGF-  as a marker of FMD.

FMD Fact Sheet

Basic facts about FMD - information is held within a PDF document supplied by FMDSA

January 31, 2014

Tope 8 Lesson Learned

Top 8 Lessons Laerned From the US Registry for FMD

Understanding the impact of registry data on clinical practice.

By Sarah O’Connor; Jeffrey W. Olin, DO; and Heather L. Gornik, MD

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A Library of public domino FMD related reports and data

The following documents, reports and posters have been collected and will continue to be collected and updated, looking to provided FMD suffered and others with a single point of reference for as much FMD related documentation as possible.